How to use umod1/8/2023 It is not derived from blood plasma but is produced by the thick ascending limb of the loop of Henle of the mammalian kidney. These two represent the major variants of this gene and encode the same isoform. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. The human UMOD gene is located on chromosome 16. Uromodulin is the most abundant protein excreted in ordinary urine. Uromodulin ( UMOD), also known as Tamm–Horsfall protein ( THP), is a Zona pellucida-like domain-containing glycoprotein that in humans is encoded by the UMOD gene.
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